Title of article :
Some Haematological Parameters in Rabbits Treated With Methanolic Extract of Garcinia Kola
Author/Authors :
Osifo, U. C. Ambrose Alli University - College of Medicine - Department of Physiology, Nigeria , Ozor, M. O. Ambrose Alli University - College of Medicine - Department of Physiology, Nigeria , Akpamu, U. Ambrose Alli University - College of Medicine - Departments of Physiology, Nigeria , Idehen, I. C. Ambrose Alli University - College of Medicine - Departments of Physiology, Nigeria
Abstract :
This study investigates the effect of methanolic extract of Garcinia kola on some haematological parameters of adult male rabbits. The rabbits (1.55kg) were assigned into two groups; A (control, n = 10) and B (experimental, n = 10). In addition to water and feed given ad libitum, the experimental group received 100mg/day of methanolic extract of Garcinia kola for 4weeks. At the end of the experiment, blood was obtained for assessment of the data herein presented. Results (paired sample t-test) as judge against with the control values presented significant reduction (p 0.05) in the values of PCV, Hb, neutrophil and eosinophil counts, a significant increased (p 0.05) in the WBC and lymphocyte counts and an unchanged monocyte and basophil counts. Considering the clinical significant of the haematological changes (PCV and Hb) that were presented, excessive ingestion of Garcinia kola therefore, is not without negative effects to well-being.
Keywords :
Garcinia kola , hematological parameters , herbal medicine , male , rabbits
Journal title :
African Journal of Biomedical Research
Journal title :
African Journal of Biomedical Research