Title of article
Promoted Preparation of Aminophosphonate and Functionalized Coumarins Derivatives as Key Constituent of Many Pharmaceutical Compounds
Author/Authors
Mohammadi, Helia Department of Chemistry - Karaj Branch - Islamic Azad University , Mohtat, Bita Department of Chemistry - Karaj Branch - Islamic Azad University , Kordtabar, Mehran Department of Chemistry - Karaj Branch - Islamic Azad University
Pages
9
From page
31
To page
39
Abstract
The reaction between trialkyl phosphites with dialkyl actylenedicarboxylates in the presence of 2-hydroxyquinoline (2-quinolinol) leads to β-aminophsphonates derivatives which they have many applications in medicinal chemistry. When the reaction was performed by triphenylphosphite, a new pyrano quinoline compounds were obtained in fairly good yields. These compounds also provide biologically interesting. All roducts were established by IR, NMR (1H,13C and31P),mass spectroscopy and elemental analysis.
Keywords
β-aminophsphonates , Coumarins , Trialkyl (aryl) phosphate , 2-quinolinol , Dialkyl actylenedicarboxylates
Journal title
Quarterly Journal of Applied Chemical Research (JACR)
Serial Year
2020
Record number
2532758
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