Title of article :
A one-pot efficient four-component reaction for the synthesis of 2-(arylamino)-2-(5-aryl-1-ethenyl-1,3,4- oxadiazol-2-yl)propyl benzoate (or 4-bromobenzoate) derivatives
Author/Authors :
VALIZADEH HOLAGH, Mohsen Baku State University - Chemistry Department, AZERBAIJAN , MAHARRAMOV, Abel Mohammadalioglu Baku State University - Chemistry Department, AZERBAIJAN , ALLAHVERDIYEV, Mirza Ali akbaroglu Baku State University - Chemistry Department, AZERBAIJAN , RAMAZANI, Ali zanjan university - Department of Chemistry, زنجان, ايران , AHMADI, Yavar islamic azad university - Young Researchers Club, ايران , ZEINALI NASRABADI, Fatemeh zanjan university - Department of Chemistry, زنجان, ايران , SOULDOZI, Ali islamic azad university - Chemistry Department, ايران
Abstract :
Reactions of N -isocyaniminotriphenylphosphorane with 2-oxopropyl benzoate (or 2-oxopropyl 4-bromobenzoate) in the presence of 3-phenyl-2-propynoic acid and primary amines proceeded smoothly at room temperature and in neutral conditions to afford sterically congested 1,3,4-oxadiazole derivatives in high yields. The reaction proceeded smoothly and cleanly under mild conditions and no side reactions were observed.
Keywords :
2 , Oxopropyl benzoate , 2 , oxopropyl 4 , bromobenzoate , 3 , phenyl , 2 , propynoic acid , 1 , 3 , 4 , oxadiazole , N , isocyaniminotriphenylphosphorane
Journal title :
Turkish Journal of Chemistry
Journal title :
Turkish Journal of Chemistry