Title of article
Calixpenams: synthesis, characterization, and biological evaluation of penicillins V and X clustered by calixarene scaffold
Author/Authors
NASUHI PUR, Fazel urmia university - Faculty of Science - Department of Chemistry, اروميه, ايران , NASUHI PUR, Fazel urmia university of medical sciences - Health Technology Incubator Center, ايران , AKBARI DILMAGHANI, Karim urmia university - Faculty of Science - Department of Chemistry, اروميه, ايران
From page
288
To page
296
Abstract
Four 6-aminopenicillanic acid moieties were grafted at either rim of calix[4]arene, giving 2 novel generations of penicillin, which were named calixpenam. Antibiotic tests showed that they have amplified activity with respect to the corresponding penams against 3 gram-positive nonpenicillinase-producing strains of Streptococcus.
Keywords
Calixpenam , Calixarene , 6 , aminopenicillanic acid , nonpenicillinase , Streptococcus strains
Journal title
Turkish Journal of Chemistry
Journal title
Turkish Journal of Chemistry
Record number
2533338
Link To Document