Title of article :
Antioxidant, anticholinesterase, and antimicrobial activities and fatty acid constituents of Achillea cappadocica Hausskn. et Bornm.
Author/Authors :
ERTAŞ, Abdulselam Dicle University - Atatürk High School of Health, Turkey , BOǦA, Mehmet Istanbul University - Faculty of Pharmacy - Department of General and Analytical Chemistry, Turkey , HAŞİMİ, Nesrin Batman University - Faculty of Arts and Science - Department of Biology, Turkey , YEŞİL, Yeter Istanbul University - Faculty of Pharmacy - Department of Pharmaceutical Botany, Turkey , GÖREN, Ahmet Ceyhan TÜRKİYE BİLİMSEL ve TEKNOLOJİK ARAŞTIRMA KURUMU (TÜBİTAK UME) - National Metrology Institute - Chemistry Group Laboratories, Turkey , TOPCU, Gülaçtı Bezmialem Vakıf University - Faculty of Pharmacy - Department of Pharmacognosy and Phytochemistry, Turkey , KOLAK, Ufuk Istanbul University - Faculty of Pharmacy - Department of General and Analytical Chemistry, Turkey
Abstract :
This study was the first fatty acid analysis and biological activity report on an endemic Achillea species, Achillea cappadocica Hausskn. et Bornm. The major compounds in the fatty acid were identified as oleic (34.7%), palmitic (23.1%), and linoleic acids (20.6%). The methanol and water extracts indicated higher ABTS cation radical scavenging activity than that of α -tocopherol and BHT at 100 µg/mL. The acetone extract showed 70.62% inhibitory activity against butyrylcholinesterase at 200 µg/mL. The acetone and methanol extracts exhibited moderate antimicrobial activity.
Keywords :
Asteraceae , Achillea cappadocica , fatty acid , antioxidant , anticholinesterase , antimicrobial
