Title of article :
In Vitro Antibacterial Studies of Ciprofloxacin-imines and Their Complexes with Cu(II),Ni(II),Co(II), and Zn(II)
Author/Authors :
IMRAN, Muhammad University of the Punjab, PAKISTAN , IQBAL, Javed Punjab University - Institute of Chemistry, PAKISTAN , IQBAL, Shahid University of Sargodha - Department of Chemistry, PAKISTAN , IJAZ, Nazia University of Sargodha - Department of Chemistry, PAKISTAN
Abstract :
Some new transition metal complexes of ciprofloxacin-imines derived from ciprofloxacin and p-substituted anilines were synthesized and characterized on the basis of physical properties, conductance measurements, elemental analysis, UV/Vis., infraredand nuclear magnetic resonance spectroscopy. These ligands as well as their metal complexes were also evaluated for their antibacterial activity against several bacterial strains, such as Staphylococcus aureus, Bacillus subtilus, Salmonella typhae, and E. coli.It was found that metal complexes are more antibacterial as compared to uncomplexed ligands. The present study was carried outin search of a target antibiotic instead of a broad spectrum one.
Keywords :
Ciprofloxacin imines , coordination compounds , antibacterial activity
Journal title :
Turkish Journal of Biology
Journal title :
Turkish Journal of Biology
