Title of article :
Antipyretic Activity of Peperomia pellucida Leaves in Rabbit
Author/Authors :
KHAN, Alam University of Rajshahi - Department of Pharmacy, BANGLADESH , RAHMAN, Moizur University of Rajshahi - Department of Animal Husbandry and Veterinary Science, BANGLADESH , ISLAM, Shariful University of Rajshahi - Department of Animal Husbandry and Veterinary Science, BANGLADESH
Abstract :
Antipyretic effects of petroleum ether and ethyl acetate soluble fractions of ethanol extract of the leaves of Peperomiapellucida (Linn.) HBK (Fam. Piperaceae) were investigated. Intraperitoneal administration of boiled milk at a dose of 0.5 ml/kg bodyweight in albino rabbit leads to pyrexia. Intraperitoneal (i.p.) administration of petroleum ether and ethyl acetate soluble fractionsof ethanol extract of the leaves of P. pellucida at a dose of 80 mg/kg body weight significantly reduced the elevated bodytemperature of rabbit. This antipyretic effect has been compared with antipyretic effect of standard aspirin and the solvent used.
Keywords :
Peperomia pellucida , leaves , antipyretic , rabbits , boiled milk , aspirin
Journal title :
Turkish Journal of Biology
Journal title :
Turkish Journal of Biology
