Author/Authors :
Ghasemi Sakha, Fatemeh Department of Biology - Damghan Branch - Islamic Azad University, Damghan , Moazzeni, Mohammad Department of immunology - Tarbiat Modares University, Tehran , Etesam, Farnaz Psychosomatic Medicine Research Center - Imam Khomeini Hospital - Tehran University of Medical Sciences, Tehran , Azimi Saeen, Amirreza MS Research Center - Neuroscience Institute - Tehran University of Medical Sciences, Tehran , Vaezi, Gholamhassan Department of Biology - Damghan Branch - Islamic Azad University, Damgha
Abstract :
The goal in studies concerning biomarkers in autoimmune diseases is finding
a marker which fluctuates in correlation with the disease’s severity and settles
within normal borders after effective treatment. This marker would later be used as
an efficient tool in diagnosis and analysis of medicine clout. It seems the most
cogent biomarkers are those measurable in serum or plasma. MS is a neurological
disease common within the young adult population with a predictable course, often
leading to life-immersing disability. The prognosis, however difficult and limited,
is currently possible via diagnostic tests (brain MRI) or clinical information
(severity and degrees of disability). Many studies have been conducted in an effort
to detect an adequate biomarker. It is still often overlooked that a reliable biomarker
should both be clinically applicable and functional is prognosis; as this is what
could lead to timely treatment.
Keywords :
MS biomarkers , Autoimmune disease , Demyelination , Micrornas
