Title of article
Antiprotozoal Activity of α, β-Unsaturated δ-Lactones: Promising Compounds for the Development of New Therapeutic Alternatives
Author/Authors
Wilson, Cardona G. Universidad de Antioquia - Instituto de Química, Química de Plantas Colombianas, Colombia , Jairo, Saez V. Universidad de Antioquia - Instituto de Química, Química de Plantas Colombianas, Colombia
From page
671
To page
680
Abstract
The parasite resistance and side effects of drugs used to treat protozoal diseases have led to the search for new therapies, both natural and synthetic. Studies have shown that various α,β-unsaturated δ- lactones displayed high antiprotozoal activity and thus are promising compounds for new drug discovery and development. These compounds and their activity are examined in this review.
Keywords
Lactones , Pyrones , Antiparasitic , Antiprotozoal , Leishmania , Malaria , Chagas , Plasmodiumfalciparum , Tripanosoma cruzi.
Journal title
Tropical Journal of Pharmaceutical Research
Journal title
Tropical Journal of Pharmaceutical Research
Record number
2536085
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