Title of article :
Antimicrobial effects of some herbal extracts against infectious bacteria isolated from burn wound
Author/Authors :
mohammadsadeghi, shahin shahid beheshti university of medical sciences - school of medicine - plastic surgery ward, Tehran, Iran , habibi, hassan persian gulf university - agricultural and natural resources college, Bushehr, Iran , keshavarzi, abdolkhalegh shiraz university of medical science - burn and wound healing research center, Shiraz, Iran , malekpour, abdorrasoul legal medicine organization - legal medicine research center, Tehran, Iran
Abstract :
Herbal compounds with antimicrobial effects are of major importance because of increasing antimicrobial resistance of pathogenic bacteria. In this study, we investigated the antimicrobial effects of Melissa officinalis L, Plantago major L, Orobancha crenata Forsk, Phoenix dactylifera, Ziziphus mauritiana, and Teucrium polium seed extracts on some human pathogenic bacteria isolated from burn wounds. Disk-diffusion antibiotic sensitivity testing, Minimum Inhibitory Concentration (MIC), and Minimum Bactericidal Concentration (MBC) were applied to assess the antibacterial activity of the extracts in comparison with tetracycline, as a control antibiotic. The extract of the Orobancha crenata showed stonger antibacterial effects than the other herbal extracts on Pseudomonas aeroginosa and Kelebsiela ponomoni. Staphylococcus aureus was the most sensitive one to the Ziziphus mauritiana nucleus extract compared with other herbs. According to the results of this study, it can be concluded that the extracts of some native plants of Iran can be an appropriate alternative to the existing antibiotics, applicable for prevention of burn infections.
Keywords :
Antimicrobial , Burn infections , Burn wound , Herbal extract , Pathogenic bacteria
Journal title :
Trends in Pharmaceutical Sciences
Journal title :
Trends in Pharmaceutical Sciences