The Effect of Ferric Chloride on Superficial Bleeding

ResultsThe hemostasis time for the ferric chloride concentration group was significantly less than for the control group (P 0.001). Materials and MethodsIn this animal model study, 60 male Wistar rats were used. An incision, 2 cm long and 0.5 cm deep was made on rat skin and the hemostasis time was recorded using ferric chloride at different concentrations (5%, 10%, 15%, 25%, and 50%) and then using a control (i.e. control of bleeding by suturing). The skin tissue was examined for pathological changes. Finally, the obtained data were entered into SPSS (ver. 16) and analyzed using Kruskal-Wallis test, Mann-Whitney, Kolmogorov-Smirnov, and Wilcoxon signed ranks test.ObjectivesThis study assesses the hemostatic effects of ferric chloride and compares it with the standard method (suturing technique) to control superficial bleeding.BackgroundControlling superficial bleeding, despite all the progress in surgical science, is still a challenge in some settings.ConclusionsFerric chloride may be an effective hemostatic agent to control superficial bleeding in rats.