Title of article :
Urinary Monocyte Chemoattractant Protein-1 (MCP-1) Correlates with Parameters of Renal Injury in Type II Diabetes Mellitus
Author/Authors :
IBRAHIM, SALWA Cairo University - Faculty of Medicine - Department of Medicine, Egypt , RASHED, LAlLA Cairo University - Faculty of Medicine - Department of Medical Biochemistry, Egypt
Abstract :
Introduction: Diabetic nephropathy (DN) is the leading cause of end stage renal disease in western world. Increased number of interstitial macrophages has been observed in biopsies from patients with DN. Monocyte chemoattractant protein-1 (MCP-1) is the strongest known chemotactic factor for monocytes and is upregulated in DN. We examined urinary level of MCP-1 in type 2 DM patients to assess the possible correlation between its level and the parameters of renal injury.
Keywords :
Monocyte chemoattractant protein , Diabetes , Renal injury
Journal title :
The Medical Journal of Cairo University
Journal title :
The Medical Journal of Cairo University
