Author/Authors :
FARGHALY, MARWA Cairo University Hospital - Department of Neurology, Egypt , HUSSEIN, MONA Beni Seuif University Hospital - Department of Neurology, Egypt , HINDY, ODETTE W. Cairo University Hospital - Center of Genomic Medicine, Egypt , KORAA, SOHAIR National Center for Radiation Research and Technology - Department of Radiation Health, Egypt , HASSAN, AZZA A.H. Cairo University Hospital - Department of Neurology, Egypt
Abstract :
Introduction: The role of plasma amyloid beta level as a biomarker for Alzheimer’s disease has attracted many researchers to explore yet its relation to cognitive functions in elderly is still not explored.Objectives: To find relation between plasma amyloid beta level and cognitive functions in normal elderly. Hence, test the value of plasma amyloid beta levels as a biomarker of cognitive functions in non-demented elderly. Subjects and methods: This is an observational cross-sectional study conducted on thirty eight non demented Egyptian subjects. Subjects included in this study were subjected to Global assessment of cognitive function and to assessment of specific cognitive domains. Plasma amyloid beta 42 level was measured.Conclusion: Plasma amyloid beta levels are not related to cognitive performance in non demented elderly.
