Evaluation of OCT Morphological Pattern in Prediction of Visual Outcome after Pars Plana Vitrectomy with ILM Peeling for Persistent Diffuse Nontractional Diabetic Macular Edema

Aim of Study: To assess the correlation between the OCT morphological pattern of macular edema and improvement of macular thickness and visual acuity following pars plana vitrectomy and ILM peeling for diffuse non-tractional diabetic macular edema. Methods: 25 eyes with persistent diabetic macular edema were treated with 23 guage transconjunctival PPV with ILM peeling. Pre-operative evaluation performed including full medical and ophthalmological history and examination. Central Subfield Macular Thickness (CSMT) and Best Cor-rected Visual Acuity (BCVA) was evaluated at 6 weeks and 3 months and 6 months post-operatively. Results: Mean pre-operative CSMT was 536.56µ (SD± 134.064) which was highest for Serous Retinal Detachment (SRD) group. Mean post-operative CSMT was 395.44µ (SD ±102.844), 359.16µ (SD±116.005), 321.8µ (SD±111.233) at 6 weeks, 3 months and 6 months respectively. The mean change in CSMT was –141.12µ (SD ±122.588), –177.4µ (SD ±127.343) and –214.76µ (SD±124.331) at 6 weeks, 3 months and 6 months respectively. This was statistically significant (p-value 0.0001). This change was highest for Diffuse Retinal Thickening (DRT) group at 6 months and the change in CSMT is statistically significant in all groups at different follow-up visits (p-value 0.05).