Study of Synergistic Effect of Allicin with Antibacterials Against Micro-organisms

Background: This study was designed to observe the antibacterial activity of allicin in combination with antibacterials, ciprofloxacin, enoxacin, vancomycin and clarithromycin against microorganisms pseudomonas aureginosa and staph aureus.Study Design: It is an analytical study.Materials and methods: Allicin was extracted from garlic with ethanol and chloroform. It was isolated by filteration technique using 15 mm Hg of pressure. Antibiotic discs were taken and micro-organisms were obtained from pathology lab FJMC LHR, Antibacterial activity of allicin was observed in combination with antibiotics.Results: It was found from the study that there is strong synergistic effect of allicin in combination with ciprofloxacin and enoxacin against pseudomonas aureginosa. Allicin also showed synergistic antibacterial effect with vancomycin and clari-thromycin against staph aureus.Conclusion: Due to the increasing resistance developed by microorganisms against the antibiotics, it may be suggested that the use of allicin along with antibiotics may overcome this resistance