Frequency of Fetal Distress in Labour Induced with Mesoprostol in Comparison with Dinoprostone in Tertiary Care Hospital

Objective: The aim of this study was to compare the frequency of fetal distress in patients induced with Mesoprostol versus Dinoprostol administered at 6 hourly intervals. Design: Cross – sectional comparative study. Setting: This study was conducted at a tertiary care teaching hospital, Lady Aitcheson Hospital, Lahore. Patients and Methods: A total of 200 patients, all primigravidas between 18 – 35 years of age undergoing induction at 41 weeks with alive pregnancy and an unfavorable Bishop Score, were included in this study. They were randomly divided into Misoprostol and Dinoprostone group, each containing 100 patients. Those postdates primigravidas were selected who have no evidence of any medical disorder or evidence of Intra Uterine Growth Retardation (IUGR). Results: Out of Mesoprostol group 38% patients delivered vaginally and 62 % emergency caesarean sections were done with fetal distress in 35 patients. And in Dinoprostone group 40% patients were delivered Gulab Devi Postgraduate Medical Institute, Lahore vaginally and 60% emergency caesarean sections were done with fetal distress in 40 patients. Conclusion: The incidence of fetal distress is significant when different inducing agents are used for induction of labor in patients with the same indication. Mesoprostol may be a better option in under developing country like ours, because it is cheep, easy to store, easily available, safe to administer and is not difficult to follow the patient after its use.