Author/Authors :
Nikeghbalian, Saman shiraz university of medical sciences - Shiraz Transplant Research Center, ايران , Mehdi, Haider shiraz university of medical sciences - Shiraz Transplant Research Center, ايران , Aliakbarian, Mohsen shiraz university of medical sciences - Shiraz Transplant Research Center, ايران , Aliakbarian, Mohsen mashhad university of medical sciences - Surgical Oncology Research Center, Imam Reza Hospital, Faculty of Medicine, ايران , Kazemi, Kourosh shiraz university of medical sciences - Shiraz Transplant Research Center, ايران , Shamsaeefar, Alireza shiraz university of medical sciences - Shiraz Transplant Research Center, ايران , Bahreini, Amin shiraz university of medical sciences - Shiraz Transplant Research Center, ايران , Gholami, Siavash shiraz university of medical sciences - Shiraz Transplant Research Center, ايران , Malekhosseini, Ali shiraz university of medical sciences - Shiraz Transplant Research Center, ايران
Abstract :
Liver transplant can be challenging in cirrhotic patients with diabetes mellitus. In chronic liver disease, the glucose metabolism is altered; uncontrolled diabetes negatively inluences the outcome of liver transplantation and poses difficulty in the management of immediate post transplantation period. Simultaneous liver-pancreas transplantation is an option to prevent early complications due to diabetes and also to improve the quality of life after transplantation in patients with Insulin-Dependent Diabetes Mellitus (IDDM) and chronic liver disease. We report the first en-bloc liver-pancreas transplant done in the transplant history of Iran. We describe the technical details of the procedure as well as the short term outcome after transplantation. In this case report, we also discuss in some details, the surgical, medical and im- munological advantages of combined liver-pancreas transplantation as opposed to separate implantation of both organs.
Keywords :
cirrhosis , diabetes mellitus , en , bloc , liver , pancreas , transplantation
