Author/Authors :
Yin, Xiuyun Affiliated Hospital of Academy of Military Medical Sciences - Department of laboratory of Medicine, China , Li, Yuhang Affiliated hospital of Academy of Military Medical Sciences - Center of Hematopoietic Stem Cell Transplantation, China , Zeng, Lijun Affiliated Hospital of Academy of Military Medical Sciences - Department of laboratory of Medicine, China , Yu, Nong Affiliated Hospital of Academy of Military Medical Sciences - Department of laboratory of Medicine, China , Song, Shiping Affiliated Hospital of Academy of Military Medical Sciences - Department of laboratory of Medicine, China , Zhang, Wei Affiliated Hospital of Academy of Military Medical Sciences - Department of laboratory of Medicine, China , Chen, Jiankui Affiliated Hospital of Academy of Military Medical Sciences - Department of laboratory of Medicine, China , Jun, Wang Affiliated hospital of Academy of Military Medical Sciences - Center of Hematopoietic Stem Cell Transplantation, China , Hu, Liangding Affiliated hospital of Academy of Military Medical Sciences - Center of Hematopoietic Stem Cell Transplantation, China , Chen, Shuiping Affiliated Hospital of Academy of Military Medical Sciences - Department of laboratory of Medicine, China
Abstract :
We reported a typical brucellosis, which was diagnosed as hemophagocytic lymphohistiocytosis (HLH). Although some tumor markers (CEA, CYFRA21-1, NSE, CA19-9) in the patient s serum were elevated, carcinomas were excluded by a variety of inspections including bone marrow aspirations, ultrasound examinations, and whole-body PET-CT scans. It was concluded that serum tumor markers are considered medically necessary as a screening test for brucellosis with HLH, however, detailed inspections were needed to make a final diagnosis. Moreover, combination of epidemiology investigations and laboratory inspections were helpful to determine the etiology of HLH and initiate the corresponding treatments.
