Case Series of Hepatoblastoma

Background: In the past 20 years, a dramatic improvement in the prognosis of patients with hepatoblastoma (HB) has been achieved by combining surgery and chemotherapy in several national and international trials. Materials and Methods: Four children ( 3 girl and 1 boy) aged 34 days, 4 months, 13 months, and 1 year with mean age of 6.53 (±5.15) months were presented to our center from 2002 to 2009 with abdominal mass and abdominal distention. Their abdominal ultrasonography revealed liver mass, and pathological diagnosis was hepatoblasma. They were treated with a combination of surgery and chemotherapy. Results: Patients with non-metastatic HB were treated at Shahid Sadoughi Hospital of Yazd. A complete resection of primary tumor was achieved in all of them. The median follow- up of the patients was 38.25 (± 29.02) month and all of them (100%) remained alive with complete remission. Conclusion: Complete resection with chemotherapy can improve prognosis of hepatoblastoma patients.