Title of article :
Nano-Silica phosphoric acid: an efficient catalyst for one-pot synthesis of 3,4-dihydropyrimidin-2(1H)-ones (thiones) under solvent-free or sonication conditions
Author/Authors :
Bamoniri, Abdolhamid university of kashan, كاشان, ايران , Mirjalili, Bi Bi Fatemeh yazd university, يزد, ايران , Nazemian, Sedigheh
Abstract :
Two simple protocols for the synthesis of three-component condensation reaction of an aldehyde, B-ketoester and urea or thiourea to obtain the 3, 4-dihydropyrimidin-2(1H)-ones (thiones) using nano silica phosphoric acid are reported. Short reaction times, high yields, reusability of catalyst and easy workup are some advantages of these protocols.
Keywords :
Biginelli reaction , Dihydropyrimidin , 2(1H) , ones , Dihydropyrimidin , 2(1H) , thiones , Heterogeneous catalyst , Multi , component reactions , Nano silica phosphoric acid , Sonication condition ,
Journal title :
Iranian Journal of Catalysis
Journal title :
Iranian Journal of Catalysis
