Author/Authors :
Khazdooz, Leila islamic azad university, ايران , Zarei, Amin islamic azad university, ايران , Hajipour, Abdol R Dept. of Pharmacology, University of Wisconsin, Medical School, Madison, 53706-1532, WI, USA, USA , Sheikhan, Nafisehsadat islamic azad university, ايران
Abstract :
An efficient, mild and environmentally friendly method was developed for the Strecker reaction to synthesize ?-aminonitriles in the presence of methyl imidazolium hydrogen sulfate ([Hmim][HSO4]) as an efficient catalyst. These syntheses were performed via a one-pot three-component condensation of aldehydes (or ketones), amines, and trimethylsilyl cyanide under mild and solvent free conditions
Keywords :
Strecker , Alpha , Amino nitriles , Methyl imidazolium hydrogen sulfate , Solvent free conditions ,
