Title of article
Three phenolic glycosides and immunological properties of Achillea millefolium from Iran, population of Golestan
Author/Authors
Yassa, N. tehran university of medical sciences tums - Faculty of Pharmacy - Department of Pharmacognosy, Medicinal Plant Research Center, تهران, ايران , Saeidnia, S. tehran university of medical sciences tums - Faculty of Pharmacy and Medicinal Plant Research Center - Department of Pharmacognosy, تهران, ايران , Pirouzi, R. islamic azad university - Faculty of Pharmacy, ايران , Akbaripour, M. tehran university of medical sciences tums - Faculty of Pharmacy and Medicinal Plant Research Center - Department of Pharmacognosy, تهران, ايران , Shafiee, A. tehran university of medical sciences tums - Faculty of Pharmacy and Pharmaceutical Sciences Research Center - Department of Medicinal Chemistry, تهران, ايران
From page
49
To page
52
Abstract
From MeOH extract of aerial parts of Achillea millefolium L. collected from Golestan province of Iran, three glycosylated phenolic compounds, luteolin 7-O-glucoside, apigenin 7-O-glucoside and caffeic acid glucoside were isolated and identified by spectroscopic analyses. Immunological properties of different fractions of plant extract were studied on humoral immune system of BALB/c mice by Microhaemagglutination test. Among these fractions only two fractions at 125 mg kg-1 and 61.5 mg kg-1 showed a significant decrease in the anti- SRBC titer of mice (P 0.05). The immunological properties of the latter fractions may be due to glycosylated derivatives of caffeic acid.
Keywords
Achillea millefolium , Asteraceae , Flavonoids , Humoral Immune System
Journal title
Daru:Journal of Pharmaceutical Sciences
Journal title
Daru:Journal of Pharmaceutical Sciences
Record number
2551672
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