Title of article :
Antimicrobial activity of Iranian propolis and its chemical composition
Author/Authors :
Yaghoubi, S.M.J. isfahan university of technology - College of Agriculture - Department of Animal Sciences, اصفهان, ايران , Ghorbani, G.R. isfahan university of technology - College of Agriculture - Department of Animal Sciences, اصفهان, ايران , Soleimanian Zad, S. isfahan university of technology - College of Agriculture - Department of Food Sciences and Technology, اصفهان, ايران , Satari, R. isfahan university of technology - College of Agriculture - Department of Food Sciences and Technology, اصفهان, ايران
Abstract :
The objective of this study was to investigate the antimicrobial activity of ethanol extract of Iranian propolis on some microorganisms using disc diffusion method. The chemical composition of the propolis was also investigated using thin layer chromatography and spectrophotometric methods. Ethanol extract of propolis showed activity only against Gram-positives and fungi, whereas no activity was observed against Gram-negatives. Thin layer chromatography screening revealed the presence of pinocembrine, caffeic acid, kaempferol, phenethyl caffeate, chrysin, and galangin in Iranian propolis. The total flavonoid and phenolic contents were 7.3% and 36%, respectively, which suggests that the strong antimicrobial activity of Iranian propolis may be due to high levels of phenolic and flavonoid compounds.
Keywords :
Iranian propolis , Phenolic compounds , Flavonoid compond
Journal title :
Daru:Journal of Pharmaceutical Sciences
Journal title :
Daru:Journal of Pharmaceutical Sciences
