Title of article :
Two new imidazole alkaloids from Leucetta chagosensis sponge
Author/Authors :
Hassan, Wafaa H.B. King Saud University - College of Pharmacy - Department of Pharmacognosy, Saudi Arabia , Al-Taweel, Areej M. King Saud University - College of Pharmacy - Department of Pharmacognosy, Saudi Arabia , Proksch, Peter Heinrich-Heine-Universitat Dusseldorf - Institut fur Pharmazeutische Biologie, Germany
Abstract :
Chemical investigation of the sponge Leucetta chagosensis, has led to the isolation of two new imidazole alkaloids, methyldorimidazole (1), preclathridine B (2) along with the known com- pounds naamine E (3) and leucettamine C (4). The structures of the newly compounds (1 and 2) were elucidated by employing spectroscopic techniques (1H NMR, MS and UV). The structures of the known compounds 3 and 4 were determined by comparison of their 1H NMR and Mass spec- troscopic data with published values.
Keywords :
Leucetta chagosensis , Imidazole alkaloids , Methyldorimidazole , Preclathridine B
Journal title :
Saudi Pharmaceutical Journal(SPJ)
Journal title :
Saudi Pharmaceutical Journal(SPJ)
