• Title of article

    A Study Towards the Total Synthesis of TAN1251B(Kajian bagi Mensintesis TAN1251B Secara Menyuluruh

  • Author/Authors

    ASARI, ASNUZILAWATI Universiti Malaysia Terengganu - Faculty of Science and Technology - Department of Chemical Sciences, Kuala Terengganu , HAYES, CHRISTOPHER J. University of Nottingham, University Park - School of Chemistry, United Kingdom

  • From page
    869
  • To page
    872
  • Abstract
    A synthetic route towards the synthesis of TAN1251B was developed utilizing an alkylidene carbene insertion reaction as a key step to construct the quartenary centre. The α-hydroxylation of the 5,6-spirocyclic enone with iodosobenzene was successful to give a mixture of diastereomer compounds 20 and 21 in 1:1.2 ratios.
  • Keywords
    TAN1251B , alkylidene carbene , α , hydroxylation , iodosobenzene
  • Record number

    2554801