Oxidant and antioxidant biomarkers and the risk factor of age on their concentrations in pneumonic Arabian camels (Camelus dromedarius)

The research study focused on the relationship between oxidant and antioxidant markers and trace element deficiency, especially hypocuprosis, in addition to the risk factors of significant oxidant and antioxidant markers in pneumonic Arabian camels based on their age. This study was conducted on a total of 30 adult camels which were classified into 2 groups. Group 1 included 20 apparently healthy camels free from external and internal parasites and showing no clinical signs of illness as a control group. Group 2 included 10 camels that suffered from bilateral nasal discharge, inappetence, dyspnea, cough with harsh lung sounds, which were divided according to their age into 2 subgroups. The first subgroup included pneumonic camels aged from 2-4 years, and the second subgroup included pneumonic camels aged from 5-8 years. Serum samples were collected from all camel groups during field study for mineral profile analysis and to determine the oxidant/antioxidant status. The statistical results showed a significant increase in malondialdehyde and reduced total antioxidant capacity and catalase in pneumonic camels compared to healthy ones (P< 0.01). There was a Pearson negative correlation between copper and malondialdehyde (r = - 0.6; P<0.05) in pneumonic camels ranging from 2-4 years. Young age pneumonic camels 2-4 years old were more likely to have high malondialdehyde (MDA) (OR=2.4; 95% CI=1.28-6.82; P=0.03), and low TAC concentrations (OR=3.2; 95% CI= 1.17-12.30; P=0.02).