Author/Authors :
zodzika, jana rîga stradins university - department of obstetrics and gynecology, latvia , zodzika, jana rîga eastern clinical university hospital - department of gynecology, LATVIA , rezeberga, dace rîga stradins university - department of obstetrics and gynecology, latvia , rezeberga, dace rîga eastern clinical university hospital - department of gynecology, LATVIA , donders, gilbert university of antwerp - department of obstetrics and gynecology, BELGIUM , vedmedovska, natâlija rîga stradins university - department of obstetrics and gynecology, latvia , vasina, olga rîga stradins university - department of obstetrics and gynecology, latvia , vasina, olga rîga eastern clinical university hospital - department of gynecology, LATVIA , pundure, inâra rîga stradins university - department of obstetrics and gynecology, LATVIA , bite, ruta rîga stradins university - department of obstetrics and gynecology, LATVIA , pavlova, zanna rîga stradins university - department of obstetrics and gynecology, LATVIA , zîle, oksana rîga stradins university - department of obstetrics and gynecology, LATVIA
Abstract :
The aim of the study was to determine the relations between vaginal culture results, elevated vaginal pH and abnormal vaginal microflora observed in microscopy, during the first trimester of pregnancy. A cross-sectional, observational study of 100 women receiving antenatal care in five outpatient clinics was carried out in Rîga from March 2010 until April 2011. Pregnant women at the first antenatal visit were submitted to a vaginal specimen collection for pH measurement, wet mount and cultures. Fifty pregnant women with vaginal pH 4.5 and 50 subsequent pregnant women with vaginal pH less than 4.5 were included. 96% of women with increased pH and 86% of women with normal vaginal pH showed positive cultures. Increased vaginal pH was significantly associated with M. hominis (P 0.001), U. urealyticum (P = 0.017) and E. coli (P = 0.018). Abnormal vaginal microflora patterns showed similar associations with culture findings. Multivariate logistic regression analysis showed the highest risk of abnormal vaginal microflora associated with M. hominis (OR 14.4, 95% CI 1.6–124.4, P = 0.015) and E. coli (OR 8.5, 95% CI 1.6–45.9, P = 0.013). Increased vaginal pH and abnormal vaginal microflora pattern in wet mounts was associated with M. hominis and E. coli in vaginal cultures.
Keywords :
vaginal pH , wet mount , abnormal vaginal microflora , pregnancy
