Title of article
Urinary Biomarkers of Oxidative Stress in Atrial Fibrillation
Author/Authors
Meng, Lei Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease - Department of Cardiology - Tianjin Institute of Cardiology - Second Hospital of Tianjin Medical University, China , Wong, Ricko Faculty of Medicine - The University of Notre Dame, Australia , Tsui, Man Yin Li Ka Shing Faculty of Medicine - University of Hong Kong, China , Tse, Gary Department of Medicine and Therapeutics - Chinese University of Hong Kong, China , Li, Guangping Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease - Department of Cardiology - Tianjin Institute of Cardiology - Second Hospital of Tianjin Medical University, China , Liu, Tong Tianjin Key Laboratory of Ionic-Molecular Function of Cardiovascular Disease - Department of Cardiology - Tianjin Institute of Cardiology - Second Hospital of Tianjin Medical University, China , Lip, Gregory Y. H University of Birmingham Institute of Cardiovascular Sciences - City Hospital - United Kingdom
Pages
10
From page
24
To page
33
Abstract
There is increasing evidence from molecular studies to support the role of inflammation and increased oxidative stress that produce structural and electrical atrial remodeling to produce Atrial Fbrillation (AF). Oxidative damage to cardiomyocytes yields chemical substances that are secreted in urine. These substances can serve as biomarkers that can be measured, potentially allowing clinicians to quantify oxidative damage to the heart.
Keywords
Atrial fibrillation , Oxidative stress , Urinary biomarkers , Inflammation , CRP , IL-6 , 8-OHdG , Antioxidant , NADPH oxidase , Isoprostanes
Journal title
Open Biomarkers Journal
Serial Year
2018
Record number
2559472
Link To Document