Title of article
Effects of Omental Pedicle Transposition on Regeneration of Neurotmesis Sciatic Nerve in Rabbit
Author/Authors
Al-Timmemi, H.A. Universiti Putra Malaysia - Department of Clinical Studies, Malaysia , Ibrahim, R. Universiti Putra Malaysia - Department of Clinical Studies, Malaysia , Zuki, A.Z. Universiti Putra Malaysia - Faculty of Veterinary Medicine - Department of Preclinical Studies, Malaysia , Azmi, T.I. Universiti Putra Malaysia - Faculty of Veterinary Medicine - Department of Preclinical Studies, Malaysia
From page
145
To page
150
Abstract
The present study was aimed at providing an understanding of the role of omental pedicle transposition in peripheral nerve regeneration by utilizing an established rabbit sciatic nerve regeneration model. Twelve adult New Zealand White rabbits (2-2.3kg) were divided into two groups (n=6) and acclimatized for 3 weeks. Complete blood examination, liver and kidney function tests were carried out during this period. In Group A, an end-to-end of sciatic nerve segment anastomosis was done, while that of Group B, the nerve anastomosis wrapped with omental pedicle was performed. The nerve specimens were collected from both groups for histopathological and ultrastructural evaluation after 16 weeks post surgery. Results showed that omental pedicle transpositioned (Group B) had more newly developed nerve fibres and less scar tissue. Ultrastructural examinations showed neuronal sprouting, whereas directions of regenerative nerve fibres were intraneural, but in the end-to-end anastomosis of group B showed that some of nerve fibres had extraneural
Keywords
Histopathology , nerve regeneration , omental pedicle transposition , ultrastructure
Journal title
Pertanika Journal of Tropical Agricultural Science (JTAS)
Journal title
Pertanika Journal of Tropical Agricultural Science (JTAS)
Record number
2561510
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