Title of article
Double filtration plasmapheresis in a dog with multiple myeloma and hyperviscosity syndrome
Author/Authors
Lippi, I. University of California Veterinary Medical Center - San Diego, USA , Perondi, F. Università di Pisa, Via Livornese lato monte - Dipartimento di Scienze Veterinarie, Italy , Ross, S.J. University of California Veterinary Medical Center - San Diego, USA , Marchetti, V. Università di Pisa - Dipartimento di Scienze Veterinarie, Italy , Lubas, G. Università di Pisa - Dipartimento di Scienze Veterinarie, Italy , Guidi, G. Università di Pisa - Dipartimento di Scienze Veterinarie, Italy
From page
108
To page
112
Abstract
A 12 year old, 38 kg, mix-breed, intact male dog presented with a 20 day history of clinical signs consistent with hyperviscosity syndrome secondary to multiple myeloma. The dog received three double filtration plasmapheresis treatments on day 0, 7 and 22 after presentation. A significant (p 0.05) reduction in serum total protein, alpha-2 and gamma globulins was found following each treatment. These reductions were accompanied by a complete resolution, although temporary, of the clinical signs of hyperviscosity syndrome. The present study reported for the first time the use of double filtration plasmapheresis to reduce clinical signs of hyperviscosity syndrome in a dog with multiple myeloma.
Keywords
Apheresis , Dog , Double filtration , Hyperviscosity syndrome , Multiple myeloma
Journal title
Open Veterinary Journal
Journal title
Open Veterinary Journal
Record number
2564333
Link To Document