Author/Authors :
Ozdarendeli, Aykut Firat University Medical School - Departments of Microbiology and Clinical Microbiology, Turkey , Toroman, Zulal A. Firat University Medical School - Departments of Microbiology and Clinical Microbiology, Turkey , Kalkan, Ahmet Firat University Medical School - Departments of Infectious Diseases, Turkey , Kilic, Süleyman S. Firat University Medical School - Departments of Infectious Diseases, Turkey , Ozden, Mehmet Firat University Medical School - Departments of Immunology, Turkey , Doymaz, Mehmet Z. Firat University Medical School - Departments of Microbiology and Clinical Microbiology, Turkey
Abstract :
Objectives: To study the prevalence and genotype distribution of hepatitis G virus (HGV) in hemodialysis patients in East Anatolia, Turkey. Subjects and Materials: Eighty-nine hemodialysis patients and 30 healthy individuals were analyzed by using reverse-transcriptase nested polymerase chain reaction with primers specific for 5′ untranslated region. HGV genotyping was performed by PCR and three randomly selected HGV-positive samples were sequenced. Results: Of the 89 hemodialysis patients, HGV RNA was detected in 9 (10.2%). All of our isolates were assigned to genotype 2. Conclusion: Our results showed that hemodialysis patients carry the risk for HGV infection in East Anatolia, Turkey.
Keywords :
Hepatitis G virus , Hemodialysis patients , Genotypes , East Anatolia , Turkey