Case Report: Ossifying Fibromyxoid Tumor of Soft Parts

Objective: To report a rare case of ossifying fibromyxoid tumor of soft tissue in Kuwait. Clinical Presentation and Intervention: A 60-year-old woman presented with a painless tumor, increasing in size and located in the left buttock, which had been present for an uncertain duration. The patient underwent an excisional biopsy. Pathological examination revealed a 7.5-cm well-circumscribed mass with a lobulated cut surface. Histologically, the tumor was encapsulated by an incomplete shell of lamellar bone. The tumor had variable cellularity, and, in areas, contained myxoid stroma. The tumor cells had eosinophilic cytoplasm with vesicular round-to-oval nuclei. Sparse mitoses were noted. Immunohistochemical stains demonstrated that the tumor cells expressed vimentin, S100 and neuron-specific enolase, with the latter expressed focally. Conclusion: To the best of our knowledge, this is the first case of ossifying fibromyxoid tumor of soft parts to be reported in Kuwait. Therefore, pathologists and clinicians should be aware of this tumor.