Title of article
STUDY OF TOXICITY AND HAEMAGGLUTINATING ACTIVITIY OF A PURIFIED INTRACELLULAR TOXIN AND EXTRACELLULAR CRUDE TOXIN ISOLATED FROM PSEUDOMONAS AERUGINOSA
Author/Authors
BEGUM, SHAHANARA Rajshahi Medical College - Department of Microbiology, Bangladesh , SAMSUZZAMAN, M. D. University of Rajshahi - Department of Biochemistry and Molecular Biology, Bangladesh , AHMED, IFTIKHAR Rajshahi Medical College - Department of Microbiology, Bangladesh , HASSAN, PARVEZ University of Rajshahi - Institute of Biological Sciences, Bangladesh , ABSAR, NURUL University of Rajshahi - Department of Biochemistry and Molecular Biology, Bangladesh , HAQ, JALALUDDIN A. BIRDEM - Department of Microbiology, Bangladesh
From page
171
To page
179
Abstract
The action of purified intracellular toxin (PIT) from Pseudomonas aeruginosa was examined in brine shrimp lethality bioassay. The LC50 of the PIT was calculated to be 25 μg/ml. The PIT agglutinated both albino rat and rabbit erythrocytes more potently than did extracellular crude toxin (ECT). Galactose and D-mannose, however, inhibited the agglutination property of PIT and ECT respectively. Intradermal injection of PIT caused changes on the tissues of rabbit skin at a lower dose than that of ECT.
Keywords
Pseudomonas aeruginosa toxin , Brine shrimp nauplli , Hemagglutination , Effect on rabbit tissue.
Journal title
Medical Journal of Islamic World Academy of Sciences
Journal title
Medical Journal of Islamic World Academy of Sciences
Record number
2568130
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