Title of article :
PREFORMULATION STUDY ON THE GUM OF MORINGA OLEIFERA
Author/Authors :
MADHAVI, BODDUPALLI BINDU Swami Ramananda Tirtha Institute of Pharmaceutical Sciences, India , VENNELA, KALLEM SIRI Nalanda College of Pharmacy - Department of Pharmaceutics, India , MASANA, PRASAD Nalanda College of Pharmacy - Department of Pharmaceutics, India , MADIPOJU, BHAVANA Nalanda College of Pharmacy - Department of Pharmaceutics, India
Abstract :
Preformulation study on the gum of Moringa oleifera was carried out. Various parameters like colour, odour, taste, pH and physical characteristics such as density, angle of repose, hygroscopicity, swelling index, loss on drying, total ash, insoluble matter and solubility were determined using the standard pharmacopoeial procedure. The gum was found to be hygroscopic and organoleptically acceptable. The pH was found to be 5.77 which is ideal for topical use. The gum solution exhibits non Newtonian, pseudoplastic rheological behaviour. It was found to be stable to heat, humidity, light and compatible with verapamil and propranolol hydrochloride. The gum has the potential to be used in different pharmaceutical formulations and food preparations.
Keywords :
Preformulation , Moringa oleifera , Rheology , pH , Solubility
Journal title :
Malaysian Journal of Pharmaceutical Sciences
Journal title :
Malaysian Journal of Pharmaceutical Sciences
