A study of clinical and biochemical correlation in patients of psoriasis in acute exacerbation

Objectives: To document various biochemical parameters like serum calcium, uric acid etc. and correlate them clinically. Patients and methods: An attempt was made to detect the biochemical changes during its exacerbations. Fifty biopsy proven psoriasis patients were selected. Clinical examination and the various biochemical tests were performed at the time of enrollment and at the end of eight weeks of treatment. Results: There were significant alterations in different biochemical values in patients before and after treatment. With clinical improvement there was shift of biochemical parameters towards normal value. Hyperuricemia was seen in 16% patients and hypocalcaemia was seen in 10% of patients. Conclusions: With improvement of clinical picture, a shift of biochemical values towards normal was recorded.