• Title of article

    Thyroid Stimulating Hormone Receptor

  • Author/Authors

    Tuncel, Murat Hacettepe University Faculty of Medicine - Department of Nuclear Medicine - Ankara, Turkey

  • Pages
    5
  • From page
    87
  • To page
    91
  • Abstract
    Thyroid stimulating hormone receptor (TSHR) plays a pivotal role in thyroid hormone metabolism. It is a major controller of thyroid cell function and growth. Mutations in TSHR may lead to several thyroid diseases, most commonly hyperthyroidism. Although its genetic and epigenetic alterations do not directly lead to carcinogenesis, it has a crucial role in tumor growth, which is initiated by several oncogenes. This article will provide a brief review of TSHR and related diseases.
  • Keywords
    adenoma , epigenetic alteration , thyroid cancer , Thyroid stimulating hormone receptor , genetic
  • Journal title
    Molecular Imaging and Radionuclide Therapy
  • Serial Year
    2017
  • Record number

    2575701