Title of article
Thyroid Stimulating Hormone Receptor
Author/Authors
Tuncel, Murat Hacettepe University Faculty of Medicine - Department of Nuclear Medicine - Ankara, Turkey
Pages
5
From page
87
To page
91
Abstract
Thyroid stimulating hormone receptor (TSHR) plays a pivotal role in thyroid hormone metabolism. It is a major controller of thyroid cell function and growth. Mutations in TSHR may lead to several thyroid diseases, most commonly hyperthyroidism. Although its genetic and epigenetic alterations do not directly lead to carcinogenesis, it has a crucial role in tumor growth, which is initiated by several oncogenes. This article will provide a brief review of TSHR and related diseases.
Keywords
adenoma , epigenetic alteration , thyroid cancer , Thyroid stimulating hormone receptor , genetic
Journal title
Molecular Imaging and Radionuclide Therapy
Serial Year
2017
Record number
2575701
Link To Document