Title of article :
Bone Tissue Response to Plasma Sprayed Hydroxyapatite Coatings: An In Vivo Study on Rabbit Femoral Condyles
Author/Authors :
Behnamghader, Aliasghar materials and energy research center (merc), كرج, ايران , Sharifi, Davood university of tehran - Faculty of Veterinary Medicine - Department of Clinical Sciences, تهران, ايران , Soroori, Sarang university of tehran - Faculty of Veterinary Medicine - Department of Clinical Sciences, تهران, ايران , Bagheri, Narjes Mate rials and Energy Research Center, ايران , Tolouei, Ranna islamic azad university - Science and Research Campus - Department of Biomedical Engineering, ايران , Tolouei, Ranna Mate rials and Energy Research Center, ايران , Nemati, Roghieh , Najjar, Denis Universite des Scienceset Technologies de LWe - Laboratoire de Metallurgie Physique et Genie des Maieriaux, France , Iosr, ALain Universite des Scienceset Technologies de LWe - Laboratoire de Metallurgie Physique et Genie des Maieriaux, France
From page :
57
To page :
62
Abstract :
In this study, hydroxyapatite was coated on titanium substrates by plasmaspraying process. A well-known porous and lamellar microstructure was found inthe lateral and outer surface of coating. The phase composition was studied by XRDand the morphological and the microstructural aspects were investigated by scanningelectron and optical microscopy. The hardness of coatings and substrates wasmeasured by Vickers indentation method. For in vivo study, rabbit condyles wereexposed to two groups of coated and uncoated samples. Radiographyically, differentparameters such as bone lysis, sclerosis, displacement of samples and bone resorption. were taken into consideration and no statistically differences between the twogroups, with no sign of infection on the edges of each hole were found. Histopathologicalinterpretation of all coated samples indicated that the extent of callus andthickness of speculae were quite distinct from that of uncoated group. In this group ,the space between implant and canal was filled up with matured connective tissuesand plenty of bone speculae of woven bone in nature. However, these speculaes werethinner and immature as compared to coated samples.
Keywords :
Hydroxyapatite coating, Implants , Plasma spraying.
Journal title :
Iranian Journal of Pharmaceutical Sciences (IJPS)
Journal title :
Iranian Journal of Pharmaceutical Sciences (IJPS)
Record number :
2575965
Link To Document :
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