Title of article :
Multi-component synthesis of spiro[indoline-3,4’-pyrrolo[3,4-c]pyrazoles] using Zn(BDC) metal-organic frameworks as a green and efficient catalyst
Author/Authors :
Hoseini Rad ، Masomeh Department of Chemistry - Islamic Azad University, Qom Branch , Ghasemzadeh ، Mohammad Ali Department of Chemistry - Islamic Azad University, Qom Branch , Sharif ، Mahboubeh Sadat Department of Chemistry - Faculty of Science - Islamic Azad University, Qom Branch
Abstract :
In this research, a series of spiro compounds was efficiently synthesized via onepot multi component reactions of isatins, aryl amines, dimethyl acetylenedicarboxylate and hydrazine in the presence of Zn(BDC) MOF as catalyst. The key superiority of this process is high yields, easy workup, short reaction times, and purification of the products by the nonchromatographic system. The study of the reusability of the catalyst showed that the Zn(BDC) can be readily recovered and reused six times with a slight decrease in its activity. Furthermore, the catalyst was characterized by SEM, EDX, FTIR and XRD analysis.
Keywords :
Multi , component reaction , metal–organic framework , Pyrrole , Zn (BDC) , Catalyst
Journal title :
Eurasian Chemical Communications
Journal title :
Eurasian Chemical Communications
