Title of article
Editorial: Retinoblastoma: A new challenge to the Knudson’s Dogma
Author/Authors
Karaoui, Mohamed S. King Khaled Eye Specialist Hospital - Department of Medicine, Saudi Arabia
From page
133
To page
134
Abstract
In 1971, Alfred Knudson was the first to propose the hypothesis predicting that two mutations (two hits) of keygenes in the control of cell division occurring in a retinal neuro-ectodermal cell were necessary for the development of retinoblastoma.
Journal title
Saudi Journal of Ophthalmology
Journal title
Saudi Journal of Ophthalmology
Record number
2577561
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