Title of article
Ocular metastasis of lung adenocarcinoma with ELM4-ALK translocation: A case report with a review of the literature
Author/Authors
Jiang, Kailun University of Ottawa - Ottawa Hospital, Ottawa Hospital Research Institute - Department of Ophthalmology, Department of Pathology and Laboratory Medicine, Canada , Brownstein, Seymour University of Ottawa - Ottawa Hospital, Ottawa Hospital Research Institute - Department of Ophthalmology, Department of Pathology and Laboratory Medicine, Canada , Sekhon, Harmanjatinder S. University of Ottawa - Ottawa Hospital, Ottawa Hospital Research Institute - Department of Pathology and Laboratory Medicine, Canada , Laurie, Scott A. University of Ottawa - Ottawa Hospital, Ottawa Hospital Research Institute - Department of Medical Oncology, Canada , Lam, Kay University of Ottawa - Ottawa Hospital, Ottawa Hospital Research Institute - Department of Ophthalmology, Department of Pathology and Laboratory Medicine, Canada , Gilberg, Steven University of Ottawa - Ottawa Hospital, Ottawa Hospital Research Institute - Department of Ophthalmology, Canada , Britton, William University of Ottawa - Ottawa Hospital, Ottawa Hospital Research Institute - Department of Ophthalmology, Canada
From page
187
To page
192
Abstract
Choroidal metastasis is the most common intraocular neoplasm and is associated with significant morbidity. In a small percentage of patients, ocular manifestation may be the initial presentation of a systemic malignancy and can be diagnostically difficult to distinguish from ocular primary malignancies. Herein, we present a case of a never-smoker whose ocular pathology was integral to thediagnosis and management of a lung adenocarcinoma harboring a rare oncogene. Through this case, we have explored important diagnostic and therapeutic considerations of pulmonary metastases to the choroid.
Keywords
Choroidal metastasis , Non , small cell lung carcinoma , Adenocarcinoma , EML4 , ALK translocation , Targeted therapy , Crizotinib
Journal title
Saudi Journal of Ophthalmology
Journal title
Saudi Journal of Ophthalmology
Record number
2577577
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