Title of article :
Development of novel antibacterial gel using clove and calendula extracts with colloidal silver nanoparticles
Author/Authors :
Mehraliyeva ، Sevil Department of Pharmaceutical Technology and Management - Azerbaijan Medical University , Valiyeva ، Mahbuba Department of Pharmaceutical Technology and Management - Azerbaijan Medical University , Abbasli ، Nijat Department of Pharmaceutical Technology and Management - Azerbaijan Medical University , Suleymanova ، Tarana Department of Pharmaceutical Technology and Management - Azerbaijan Medical University , Musayeva ، Sevinj Department of Pharmaceutical Technology and Management - Azerbaijan Medical University , Davaran ، Soodabeh Drug Applied Research Center - Tabriz University of Medical Sciences , Khalilov ، Rovshan Department of Biophysics and Biochemistry - Baku State University , Eftekhari ، Aziz Maragheh University of Medical Sciences
Abstract :
This study focuses on obtaining an extract from clove and calendula plants with colloidal nanoparticles of silver in the presence of 40% propyleneglycol and preparation of hydrophilic gel based on the resulting extract. Also, the optimal composition of the gel and releasing of biologically active substances from gels based on chitosan, sodium carboxymethylcellulose, carbopol, used as gelling agents was evaluated. The results showed that the release of bioactive compounds from a chitosanbased gel is more complete and intensive. The antibacterial and antifungal properties of chitosan gel containing silver nanoparticles have been confirmed by microbiological studies.
Keywords :
Antimicrobial , Antifungal , Colloidal nanoparticles , Chitosan
Journal title :
Eurasian Chemical Communications
Journal title :
Eurasian Chemical Communications
