Title of article :
Synthesis and Biological Significance of Some 2-Azetidinone Derivatives
Author/Authors :
Sharma, R. Dr. H.S. Gour University (A Central University) - Synthetic Organic Chemistry Laboratory, Department of Chemistry, India , Samadhiya, P. Dr. H.S. Gour University (A Central University) - Synthetic Organic Chemistry Laboratory, Department of Chemistry, India , Srivastava, S.D. Dr. H.S. Gour University (A Central University) - Synthetic Organic Chemistry Laboratory, Department of Chemistry, India , Srivastava, S.K. Dr. H.S. Gour University (A Central University) - Synthetic Organic Chemistry Laboratory, Department of Chemistry, India
Abstract :
A new series of N-[2-(1H-1,2,3-benzotriazol-1-yl)ethyl]-4-(substitutedphenyl)-3-chloro-2-oxo-1-iminoazetidine, compounds 4(a-j) were synthesized. The structures of all the synthesized compounds were confirmed by chemical and spectral analyses such as IR, 1H NMR, 13C NMR and FAB-Mass. The compounds 4(a-j) were screened for their antibacterial, antifungal and antitubercular activities and gave acceptable results.
Keywords :
Synthesis , 1,2,3 , Benzotriazole , Azetidinone , Antimicrobial , Antitubercular
Journal title :
Journal of Sciences Islamic Republic of Iran
Journal title :
Journal of Sciences Islamic Republic of Iran