Author/Authors :
Srivastava, A. K. University of Allahabad - Department of Chemistry, QSAR Research Laboratory, India , Pandey, Avni University of Allahabad - Department of Chemistry, QSAR Research Laboratory, India , Nath, Arpita University of Allahabad - Department of Chemistry, QSAR Research Laboratory, India , Chaurasia, Shraddha University of Allahabad - Department of Chemistry, QSAR Research Laboratory, India
Abstract :
A series of alkenyldiarylmethanes (ADAMs) were subjected to QSAR analysis by using linear free energy relationship model of Hansch. QSAR has been developed using steric, electronic and topological parameters along with appropriate dummy variable. Statistical techniques were applied to identify the structural and physicochemical requirements for ADAMs. The results are critically discussed on the basis of regression data and cross-validation techniques.
Keywords :
QSAR , Physiochemical properties , Regression analysis , Alkenyldiarylmethane analogues
