Title of article :
A novel antimicrobial triterpenic acid from the leaves of Ficus benjamina (var. comosa)
Author/Authors :
Parveen, Mehtab Aligarh Muslim University - Department of Chemistry, India , Ghalib, Raza Murad Aligarh Muslim University - Department of Chemistry, India , Mehdi, Hasan Aligarh Muslim University - Department of Chemistry, India , Mattu, Rayees Ul Hasan Aligarh Muslim University - Department of Biochemistry, India , Ali, Mohammed Jamia Hamdard - Faculty of Pharmacy, India
Abstract :
The chloroform extract of the leaves of Ficus benjamina (var. comosa) (Moraceae) afforded a new triterpenic acid named as (9,11), (18,19)-disecoolean-12-en-28-oic acid (1) along with bamyrin (2). Their structures were established on the basis of chemical and physical evidences (IR, 1H NMR, and MS data). The compound 1 exhibited significant antimicrobial activity against Salmonella typhimurium (MTCC-98), Candida albicans (IAO-109), Staphylococcus aureus (IAO-SA- 22), Escherichia coli (K-12) and low activity against Aspergillus niger (lab isolate ICAR) and Aspergillus brassicola.
Keywords :
Ficus benjamina , (Var. comosa) , Moraceae , Triterpenoids , b , Amyrin , (9,11), (18,19) , Disecoolean , 12 , en , 28 , oic acid
Journal title :
Journal of Saudi Chemical Society
Journal title :
Journal of Saudi Chemical Society
