Title of article :
Synthesis, spectroscopic and crystal structure analysis of 2-(4-fluorobenzyl)-6-(4-methoxyphenyl) imidazo[2,1-b]-[1,3,4]thiadiazole and its morpholinomethyl derivative
Author/Authors :
Banu, Afshan Bangalore University - Department of Chemistry, India , Vasundhara, D.E. Bangalore University - Department of Chemistry, India , Lamani, Ravi S. Karnatak University - Department of Chemistry, India , Khazi, I.A.M. Karnatak University - Department of Chemistry, India , Begum, Noor Shahina Bangalore University, Central College Campus - Department of Chemistry, India
Abstract :
The preparation of 2-(4-fluorobenzyl)-6-(4-methoxyphenyl)-5-morpholin-1-ylmethyl imidazo[2,1-b] [1,3,4]thiadiazole via the intermediate 2-(4-fluorobenzyl)-6-(4-methoxyphenyl)Imidazo[ 2,1-b][1,3,4] thiadiazole is described. Elemental analysis, IR spectrum, 1H NMR and X-ray crystal structure analyses were carried out to determine the compositions and molecular structures of the two compounds. The crystal packing exhibits intermolecular C–H. . .O, C–H. . .N, C–H. . .F and ᴫ–ᴫ stacking interactions leading to the formation of the supramolecular network.
Keywords :
Imidazo[2,1 , b] 1,3,4 , thiadiazoles , Crystal structure , Morpholinomethyl derivative , Weak interactions: C–H. . .O, C–H. . .N, C–H. . .F and ᴫ–ᴫ stacking
Journal title :
Journal of Saudi Chemical Society
Journal title :
Journal of Saudi Chemical Society
