Author/Authors :
Casella, Giovanni Desio General Hospital - Division of Internal Medicine, Italy , Villanacci, Vincenzo Spedali Civili - 2nd Pathology Section, Italy , Antonelli, Elisabetta University of Perugia - Gastroenterology and Hepatology Section, Department of Clinical and Experimental Medicine, Italy , Bella, Camillo Di Desio General Hospital - Pathology Unit, Italy , Baldini, Vittorio Desio General Hospital - Division of Internal Medicine, Italy , Rostami Nejad, Mohammad shahid beheshti university of medical sciences - Research Center for Gastroenterology and Liver Disease, تهران, ايران , Bassotti, Gabrio University of Perugia - Gastroenterology and Hepatology Section, Department of Clinical and Experimental Medicine, Italy
Abstract :
Inflammatory bowel disease (IBD) frequently affects young patients of childbearing age. Treatments for inflammatory bowel disease include immunosuppressive, cytotoxic and surgical therapies. Azathioprine is frequently used to treat patients with steroid dependent IBD. We report the case of a patient with ulcerative colitis, treated with azathioprine prior to conception and during the subsequent pregnancy with the subsequent successful delivery of healthy twins. Although some potential risks indeed exist, the use of AZA may not be harmful to the mother or the fetus in many instances.
Keywords :
Azathioprine , Conception , Twin pregnancy , Ulcerative colitis
