Tuberculosis and HIV Co-infection and associated factors among HIV reactive patients in Ethiopia

Context: The most common opportunistic infection among Human Immunodeficiency Virus (HIV) reactive patients is tuberculosis (TB). TB has an impact on the prognosis of the disease. However, developing countries have not paid much attention to the problem. Aims: The study was conducted with the aim of determining the level of TB/HIV co-infection and associated factors. Setting and Design: A cross sectional study design was used in Wolaita Sodo Teaching and Referral Hospital from March 15 to May 15, 2017. Materials and Methods: Three hundred and seventy three patients were selected using simple random sampling. Statistical Analysis Used: Frequencies and proportions were computed. Logistic regressions were carried out and associations were considered statistically significant at P 0.05. Results: The study revealed that 17.4% of the patients were co-infected with HIV and TB. Educational status (adjusted odds ratio [AOR] =0.472 and 95% confidence interval [CI] =0.253, 0.883), drug dependency (AOR = 2.366 and 95% CI = 1.129, 4.957), World Health Organization stage (AOR = 3.031 and 95% CI = 1.326, 6.930), and baseline CD4 (AOR = 0.351 and 95% CI = 0.153, 0.803) were predictors of the TB/HIV co-infection. Conclusion: Educational status, drug dependency, WHO clinical stage, and baseline CD4 count were found as significant predictors of co-infection. Therefore, health education about the lifestyle modification, counseling, and close monitoring of pharmacological therapy adherence is recommended.