Author/Authors :
Naved uz Zafar, M Dow University of Health Sciences - Sindh Medical College, Jinnah Medical Dental College, Dow International Medical College BMSI - Department of Pathology, Pakistan , Memon, M Arif Dow University of Health Sciences - Sindh Medical College, Jinnah Medical Dental College, Dow International Medical College BMSI - Department of Pathology, Pakistan , Agha, M Akbar Dow University of Health Sciences - Sindh Medical College, Jinnah Medical Dental College, Dow International Medical College BMSI - Department of Pathology, Pakistan , Agha, Shaheen Akbar Dow University of Health Sciences - Sindh Medical College, Jinnah Medical Dental College, Dow International Medical College BMSI - Department of Pathology, Pakistan , Hashim, Yasmeen Dow University of Health Sciences - Sindh Medical College, Jinnah Medical Dental College, Dow International Medical College BMSI - Department of Pathology, Pakistan , Mirza, Talat Dow University of Health Sciences - Sindh Medical College, Jinnah Medical Dental College, Dow International Medical College BMSI - Department of Pathology, Pakistan , Muhammad, Dur Dow University of Health Sciences - Sindh Medical College, Jinnah Medical Dental College, Dow International Medical College BMSI - Department of Pathology, Pakistan , Rizvi, Samina Dow University of Health Sciences - Sindh Medical College, Jinnah Medical Dental College, Dow International Medical College BMSI - Department of Pathology, Pakistan
Abstract :
Background: Cutaneous tuberculosis is a relatively rare clinical entity in western countries but is still prevalent in the developing world. This study was conducted to identify cases of cutaneous tuberculosis in skin lesions, study its morphology, analyse its frequency and the relative frequencies of its clinico-pathological types.Material Methods: All specimens of skin biopsy for histopathology received over a period of 5 years at the Department of Pathology, Basic Medical Sciences Institute, JPMC, Karachi were included. Morphological study was done using Ziehl Neelsen stain for acid fast bacilli and H E stain for tissue histological assessment.Results: Out of 2682 skin biopsies, 97(3.69%) were cutaneous tuberculosis. The ages ranged from 6-70 years with a mean of 28.32. Maximum number of cases (39) were in second decade. There were 37(38.14%) males and 60(61.85%) females. Out of 97 cases of tuberculosis 50 were not typified. The remaining 47 cases were typified as, 18 were lupus vulgaris, 9 verrucosa cutis, 7 each of tuberculosis cutis oroficialis and scrofuloderma and 6 were tuberculous gummas. Acid fast bacilli were seen in 20 out of 77 caseating and 1 in 20 non-caseating granulomas of tubercuclosis.Conclusion: The frequency of cutaneous tuberculosis is 3.69%. It is more prevalent in the females. Lupus vulgaris is the most common sub type of all cutaneous tuberculosis
