Author/Authors :
Shahjahan Sheikh Zayed Hospital - Department of Chemical Pathology, Department of Obstetrics Gynaecology, Pakistan , Shahjahan Quaid-e-Azam International Hospital - Department of Chemical Pathology, Pakistan , Shahjahan Gomal Medical College - Department of Biochemistry Pathology, Pakistan , Subzwari, Jawaid Gomal Medical College - Department of Biochemistry Pathology, Pakistan , Subzwari, Jawaid Sheikh Zayed Hospital - Department of Chemical Pathology, Department of Obstetrics Gynaecology, Pakistan , Subzwari, Jawaid Quaid-e-Azam International Hospital - Department of Chemical Pathology, Pakistan , Mahsood, Muhammad Amin Jan Sheikh Zayed Hospital - Department of Chemical Pathology, Department of Obstetrics Gynaecology, Pakistan , Mahsood, Muhammad Amin Jan Quaid-e-Azam International Hospital - Department of Chemical Pathology, Pakistan , Mahsood, Muhammad Amin Jan Gomal Medical College - Department of Biochemistry Pathology, Pakistan , Majid, Farah Quaid-e-Azam International Hospital - Department of Chemical Pathology, Pakistan , Majid, Farah Gomal Medical College - Department of Biochemistry Pathology, Pakistan , Majid, Farah Sheikh Zayed Hospital - Department of Chemical Pathology, Department of Obstetrics Gynaecology, Pakistan , Aslam, Faiza Quaid-e-Azam International Hospital - Department of Chemical Pathology, Pakistan , Aslam, Faiza Gomal Medical College - Department of Biochemistry Pathology, Pakistan , Aslam, Faiza Sheikh Zayed Hospital - Department of Chemical Pathology, Department of Obstetrics Gynaecology, Pakistan , Ur Rehman, Aziz Quaid-e-Azam International Hospital - Department of Chemical Pathology, Pakistan , Ur Rehman, Aziz Sheikh Zayed Hospital - Department of Chemical Pathology, Department of Obstetrics Gynaecology, Pakistan , Ur Rehman, Aziz Gomal Medical College - Department of Biochemistry Pathology, Pakistan
Abstract :
Background: Renal failure and its consequences like renal osteodystrophy is a challenge for developing countries like Pakistan. The current study was aimed to evaluate the levels of serum calcium in patients with renal failure so that renal osteodystrophies could be avoided in these patients. Methods: Total ninety subjects of both genders visiting Sheikh Zayed Hospital Lahore were selected randomly. Sixty subjects were clinically diagnosed patients of renal failure. Thirty subjects, clinically normal for kidney functions, were included in the study as control. These were classified in different age/gender based groups. Blood samples from the patients and control were analyzed in an auto-analyzer for serum calcium, serum creatinine and blood urea nitrogen. Results: Serum creatinine and blood urea nitrogen values were statistically significantly higher in the renal failure patients compare to normal subjects. Serum calcium levels were significantly lower in patients with renal failure as compared to normal subjects. Conclusion: It was concluded that positive correlation exists between serum creatinine and blood urea nitrogen. A negative correlation exist between serum creatinine, blood urea nitrogen and serum calcium levels in all group of patients with renal failure