Acute Hemorrhagic Edema of Infancy: Report of Two Cases Report

Introduction: Acute hemorrhagic edema of infancy (AHEI) is a cutaneous leukocytoclastic vasculitis of infants, clinically characterized by acute development of peripheral edema and targetoid purpuric lesions on face and extremities. It is considered to be an uncommon form of cutaneous vasculitis occurring in children younger than 2 years old.The clinical picture has a violent onset, a short benign course followed by spontaneous complete recovery.Case presentation: We describe two males with acute hemorrhagic edema. In one case the disease appeared after upper respiratory tract infection.Conclusion: AHEI is a benign disorder despite its dramatic appearance. The most striking classic features of the disease are the contrast between the acuteness of the cutaneous lesions and the good general condition of the patient. Considering its clinical features, AHEI can be justifiably characterized as a unique disorder, distinct from Henoch–Schönlein Purpura (HSP)